Long noncoding RNA s as regulators of cancer immunity
نویسندگان
چکیده
منابع مشابه
Study of Long Noncoding RNA FER1L4 and RB1, as Its Competing Endogenous RNA Network Target Gene, in Breast Cancer
Introduction: Breast cancer is the second most common cause of cancer-related death among females, which requires an exploration for markers to propose a more specific categorization of this cancer. Long noncoding RNAs (lncRNAs), the main subset of noncoding transcripts, are involved in tumorigenic processes. In this study, we investigated the expression of the fer-1–like family member 4 (FER...
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High-throughput techniques have identified numerous antisense (AS) transcripts and long non-coding RNAs (ncRNAs). However, their significance in cancer biology remains largely unknown. Here, we report an androgen-responsive long ncRNA, CTBP1-AS, located in the AS region of C-terminal binding protein 1 (CTBP1), which is a corepressor for androgen receptor. CTBP1-AS is predominantly localized in ...
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Recent advances in genome and transcriptome analysis have enabled identification of numerous members of a new class of noncoding RNA, long noncoding RNA (lncRNA). lncRNAs are broadly defined as RNA molecules greater than 200 nt in length and lacking an open reading frame. Recent studies provide evidence that lncRNAs play central roles in a wide range of cellular processes through interaction wi...
متن کاملThe Long-Noncoding RNA ELENA1 Functions in Plant Immunity.
Once seen as potential sequencing artifacts, long-noncoding RNAs (lncRNAs; >200 nucleotides) have gained recognition as important regulatory factors. lncRNAs are transcribed from a variety of genomic locations (introns, intergenic spaces, and coding regions) from the sense or antisense strand (reviewed in Chekanova, 2015). Moreover, lncRNAs function in cis or in trans and affect gene regulation...
متن کاملThe Long-Noncoding RNA ELENA1 Functions in Plant Immunity
Once seen as potential sequencing artifacts, long-noncoding RNAs (lncRNAs; >200 nucleotides) have gained recognition as important regulatory factors. lncRNAs are transcribed from a variety of genomic locations (introns, intergenic spaces, and coding regions) from the sense or antisense strand (reviewed in Chekanova, 2015). Moreover, lncRNAs function in cis or in trans and affect gene regulation...
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ژورنال
عنوان ژورنال: Molecular Oncology
سال: 2018
ISSN: 1574-7891,1878-0261
DOI: 10.1002/1878-0261.12413